Positive Feedback Loops in Alzheimer’s Disease: The Alzheimer’s Feedback Hypothesis
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چکیده
منابع مشابه
Magnesium and Alzheimers Disease: The Cholinergic Hypothesis
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A simple three-component negative feedback loop is a recurring motif in biochemical oscillators. This motif oscillates as it has the three necessary ingredients for oscillations: a three-step delay, negative feedback, and nonlinearity in the loop. However, to oscillate, this motif under the common Goodwin formulation requires a high degree of cooperativity (a measure of nonlinearity) in the fee...
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ژورنال
عنوان ژورنال: Journal of Alzheimer's Disease
سال: 2018
ISSN: 1387-2877,1875-8908
DOI: 10.3233/jad-180583